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Important Safety Information
Ozempic (Semaglutide Injection)
Prescription MedicationOzempic (semaglutide) is a once-weekly injectable GLP-1 receptor agonist. It is FDA-approved for type 2 diabetes management and widely prescribed under clinical supervision for weight management. A prescription and regular provider monitoring are required.
Emergency: If you experience chest pain, severe shortness of breath, a prolonged painful erection (over 4 hours), or sudden vision/hearing loss — call 911 or go to your nearest emergency room immediately.
Who Should Not Use Ozempic (Semaglutide Injection)
- Personal or family history of MTC or MEN 2
- Known hypersensitivity to semaglutide
- Patients with diabetic ketoacidosis (use insulin instead)
- Pregnant or breastfeeding individuals
Warnings & Precautions
Thyroid Risk
As with all semaglutide products, risk of thyroid C-cell tumors exists based on animal data. Contraindicated in those with family or personal history of MTC.
Pancreatitis
Acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, has been observed. Discontinue and do not restart if pancreatitis is confirmed.
Diabetic Retinopathy Complications
Rapid improvements in glycemic control may worsen retinopathy in diabetic patients. Ophthalmologic monitoring is recommended.
Renal Effects
Acute kidney injury has occurred due to dehydration from GI adverse events. Maintain hydration and monitor renal function.
Common Side Effects
This is not a complete list. Contact your provider if you experience any concerning symptoms.
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Decreased appetite
- Constipation
- Headache
- Fatigue
Drug Interactions
Always inform your provider of all medications, supplements, and substances you are currently taking.
- Insulin and insulin secretagogues — hypoglycemia risk
- Oral medications with narrow therapeutic windows
- Other GLP-1 receptor agonists — do not combine
When to Contact Your Provider
- Severe, persistent abdominal pain
- Rapid heart rate
- Signs of thyroid tumor
- Vision changes
- Reduced urine output or swelling suggesting kidney issues
This safety information is provided for general educational purposes only and does not constitute medical advice. It is not a substitute for the full prescribing information, package insert, or guidance from your licensed healthcare provider. Individual responses to medications and supplements vary. MEDVera providers review your complete health profile before recommending or prescribing any treatment.