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Important Safety Information
PT-141 (Bremelanotide) Injection
Prescription Peptide InjectionPT-141 (bremelanotide) is a melanocortin receptor agonist injection used to support sexual desire/arousal in men and women. It requires a valid prescription and provider evaluation, particularly of cardiovascular status, prior to use.
Emergency: If you experience chest pain, severe shortness of breath, a prolonged painful erection (over 4 hours), or sudden vision/hearing loss — call 911 or go to your nearest emergency room immediately.
Who Should Not Use PT-141 (Bremelanotide) Injection
- Individuals with uncontrolled hypertension or known cardiovascular disease
- Pregnant individuals — may harm the unborn baby
- Individuals with known hypersensitivity to bremelanotide
- Children and adolescents — safety and efficacy not established
Warnings & Precautions
Blood Pressure & Heart Rate
Bremelanotide can cause a temporary rise in blood pressure and may slow heart rate. Watch for severe headache, blurred vision, or pounding in the ears after dosing.
Cardiovascular Risk
Avoid use with uncontrolled high blood pressure or known heart disease; discuss cardiovascular history with your provider before starting.
Skin/Gum Darkening
Focal darkening of the skin, gums, face, or breasts can occur, more often with repeated use, and may not fully resolve.
Liver Effects
Rare cases of acute hepatitis/liver injury have been reported. Seek care for dark urine, yellowing skin/eyes, or right-upper abdominal pain.
Breastfeeding
Safety data during breastfeeding are limited; discuss with your provider.
Common Side Effects
This is not a complete list. Contact your provider if you experience any concerning symptoms.
- Nausea (most common, often after first dose)
- Flushing/warmth
- Headache
- Injection site reactions
- Vomiting
- Dizziness
- Fatigue
- Nasal congestion
Drug Interactions
Always inform your provider of all medications, supplements, and substances you are currently taking.
- Antihypertensive medications — additive blood pressure effects possible
- Other vasoactive or sexual-health medications — discuss combination use with your provider
When to Contact Your Provider
- Severe headache, blurred vision, chest pain, or pounding in the ears/neck (possible hypertensive reaction)
- Signs of allergic reaction: hives, facial/throat swelling, difficulty breathing
- Signs of liver injury: dark urine, pale stools, yellowing of skin/eyes
- Severe or persistent nausea/vomiting, or fainting
This safety information is provided for general educational purposes only and does not constitute medical advice. It is not a substitute for the full prescribing information, package insert, or guidance from your licensed healthcare provider. Individual responses to medications and supplements vary. MEDVera providers review your complete health profile before recommending or prescribing any treatment.