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Important Safety Information

Sermorelin (Injection / ODT)

Compounded Peptide Therapy

Sermorelin is a growth hormone-releasing hormone (GHRH) analog that stimulates the body's own natural growth hormone release, rather than supplying synthetic growth hormone directly. It is compounded and prescribed for longevity/wellness support (injection or orally-dissolving tablet) under provider supervision.

Emergency: If you experience chest pain, severe shortness of breath, a prolonged painful erection (over 4 hours), or sudden vision/hearing loss — call 911 or go to your nearest emergency room immediately.

Who Should Not Use Sermorelin (Injection / ODT)

  • Pregnant or breastfeeding individuals
  • Anyone with known or suspected malignancy (active cancer)
  • Patients with intracranial or pituitary lesions/tumors without specialist clearance
  • Individuals with known hypersensitivity to sermorelin or its components
  • Patients with uncontrolled diabetes or severe hyperglycemia without provider guidance

Warnings & Precautions

Untreated Hypothyroidism

Sermorelin's effect may be blunted by untreated hypothyroidism; thyroid function should be assessed and optimized.

Glucose Effects

May affect insulin sensitivity/blood sugar. Patients with diabetes should monitor glucose closely and discuss with their provider.

Fluid Retention

Mild fluid retention, joint aches, or carpal-tunnel-like tingling have been reported, especially at higher doses.

Limited Long-Term Data

Long-term safety data are more limited than for many standard medications; periodic provider monitoring is recommended during treatment.

Common Side Effects

This is not a complete list. Contact your provider if you experience any concerning symptoms.

  • Injection site pain, redness, or swelling (injectable form)
  • Flushing
  • Headache
  • Dizziness or drowsiness
  • Nausea
  • Restlessness
  • Rash
  • Changes in taste (oral form)

Drug Interactions

Always inform your provider of all medications, supplements, and substances you are currently taking.

  • Insulin/diabetes medications — may alter blood sugar control
  • Corticosteroids — may blunt growth-hormone response
  • Other growth-hormone-axis therapies — do not combine without provider guidance

When to Contact Your Provider

  • Signs of allergic reaction: hives, facial/throat swelling, difficulty breathing
  • New or worsening headaches or vision changes
  • Significant swelling, joint pain, or numbness/tingling in the hands
  • Blood sugar readings outside your target range

This safety information is provided for general educational purposes only and does not constitute medical advice. It is not a substitute for the full prescribing information, package insert, or guidance from your licensed healthcare provider. Individual responses to medications and supplements vary. MEDVera providers review your complete health profile before recommending or prescribing any treatment.

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