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Important Safety Information
Tadalafil (Generic Cialis)
Prescription MedicationTadalafil is the FDA-approved generic formulation of Cialis. It contains the same active ingredient (tadalafil) at identical strengths and is bioequivalent to the brand. Tadalafil is indicated for erectile dysfunction and benign prostatic hyperplasia in adult men, with up to 36 hours of effectiveness per dose. It requires a valid prescription from a licensed healthcare provider.
Emergency: If you experience chest pain, severe shortness of breath, a prolonged painful erection (over 4 hours), or sudden vision/hearing loss — call 911 or go to your nearest emergency room immediately.
Who Should Not Use Tadalafil (Generic Cialis)
- Women or children
- Men taking any form of nitrate medication
- Men taking riociguat or other soluble guanylate cyclase stimulators
- Individuals with hypersensitivity to tadalafil
- Men with severe renal or hepatic impairment (certain doses)
Warnings & Precautions
Nitrate Absolute Contraindication
Do not take tadalafil if you use nitrate medications of any kind. The combination causes potentially fatal drops in blood pressure.
Extended Duration Window
The 36-hour activity window means drug interactions or side effects can occur well after the time of dosing. Avoid nitrates for at least 48 hours after taking tadalafil.
Priapism
Erections lasting more than 4 hours are a medical emergency. Call emergency services or go to the nearest emergency room immediately.
Generic Equivalence
FDA-approved generic tadalafil has demonstrated bioequivalence to Cialis through rigorous testing. Patients can expect the same clinical performance at a significantly lower cost.
Common Side Effects
This is not a complete list. Contact your provider if you experience any concerning symptoms.
- Headache
- Back pain or muscle aches (characteristic of tadalafil vs. other PDE5 inhibitors)
- Flushing
- Indigestion
- Nasal congestion
- Dizziness
Drug Interactions
Always inform your provider of all medications, supplements, and substances you are currently taking.
- Nitrates — absolute contraindication
- Riociguat — contraindicated
- Alpha-blockers — use with caution; timing separation reduces hypotension risk
- CYP3A4 inhibitors — increase tadalafil plasma concentrations
- CYP3A4 inducers (rifampin) — reduce tadalafil effectiveness
- Moderate alcohol — may increase risk of dizziness and hypotension
When to Contact Your Provider
- Priapism (erection lasting more than 4 hours)
- Sudden vision or hearing changes
- Chest discomfort or severe dizziness during or after sexual activity
- You are prescribed nitrate medication by another provider
- You need guidance on daily versus as-needed dosing
This safety information is provided for general educational purposes only and does not constitute medical advice. It is not a substitute for the full prescribing information, package insert, or guidance from your licensed healthcare provider. Individual responses to medications and supplements vary. MEDVera providers review your complete health profile before recommending or prescribing any treatment.