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Important Safety Information
Compounded Tirzepatide Injection
Compounded Prescription MedicationCompounded tirzepatide injection contains the same dual GIP/GLP-1 receptor agonist active ingredient found in FDA-approved tirzepatide products, prepared by a licensed compounding pharmacy per an individual prescription for chronic weight management under provider supervision.
Emergency: If you experience chest pain, severe shortness of breath, a prolonged painful erection (over 4 hours), or sudden vision/hearing loss — call 911 or go to your nearest emergency room immediately.
Who Should Not Use Compounded Tirzepatide Injection
- Patients with personal or family history of MTC or MEN 2
- Known hypersensitivity to tirzepatide or any excipient
- Pregnant or breastfeeding individuals
- Patients with active gallbladder disease or severe GI disease without provider clearance
Warnings & Precautions
Thyroid C-Cell Tumors
Tirzepatide has shown dose-dependent thyroid C-cell tumors in animal studies. Contraindicated with personal/family history of MTC or MEN 2.
Pancreatitis
Discontinue and seek care immediately if persistent severe abdominal pain occurs, with or without vomiting.
Gallbladder Disease
Rapid weight loss may increase risk of gallstone formation. Report right-sided abdominal pain, nausea, or fever.
Compounding Considerations
Compounded formulations are prepared per your prescription and are not individually FDA-reviewed as a finished product; confirm dosing/concentration with your provider each fill.
Common Side Effects
This is not a complete list. Contact your provider if you experience any concerning symptoms.
- Nausea (most common)
- Diarrhea
- Vomiting
- Constipation
- Abdominal pain
- Injection site reactions
- Decreased appetite
- Fatigue
Drug Interactions
Always inform your provider of all medications, supplements, and substances you are currently taking.
- Insulin — dose reduction may be needed to reduce hypoglycemia risk
- Oral contraceptives and other oral medications affected by delayed gastric emptying
- Other GLP-1/GIP agonists — do not combine
When to Contact Your Provider
- Severe or persistent abdominal pain suggesting pancreatitis
- Symptoms of hypoglycemia if on concurrent insulin therapy
- Neck lump, dysphagia, or persistent hoarseness
- Gallbladder symptoms: right upper abdominal pain, nausea, fever
This safety information is provided for general educational purposes only and does not constitute medical advice. It is not a substitute for the full prescribing information, package insert, or guidance from your licensed healthcare provider. Individual responses to medications and supplements vary. MEDVera providers review your complete health profile before recommending or prescribing any treatment.